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KMID : 1207720200120040417
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Clinics in Orthopedic Surgery
2020 Volume.12 No. 4 p.417 ~ p.429
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Management of Osteogenesis Imperfecta: A Multidisciplinary Comprehensive Approach
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Cho Tae-Joon
Ko Jung-Min
Kim Hyoung-Min
Shin Hyung-Ik
Yoo Won-Joon
Shin Chang-Ho
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Abstract
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Osteogenesis imperfecta (OI) is characterized by recurring fractures and limb and spine deformities. With the advent of medical therapeutics and the discovery of causative genes, as well as the introduction of a newly devised intramedullary rod, the general condition and ambulatory function of patients diagnosed with OI have been improved over the past decades. This review covers recent developments in research and management of OI.
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KEYWORD
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Osteogenesis imperfecta, Gene, Bisphosphonate, Intramedullary nailing, Scoliosis
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